Abstract #0269

Portable, single-sided magnetic resonance sensor for hydration status assessment via multicomponent T2 relaxometry

Ashvin Bashyam^1,2, Chris J Frangieh^1,2, and Michael J Cima^2,3

¹Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ²David H. Koch Institute For Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States, ³Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States

Undiagnosed dehydration compromises health outcomes across many populations including the elderly, infants, soldiers and athletes. Here we introduce a miniature (~1000 cm³), portable (~4 kg), single-sided magnetic resonance (MR) sensor capable of identifying and quantifying fluid loss induced by dehydration. Multicomponent T2 relaxometry of skeletal muscle tissue enables the measurement of distinct fluid compartments. We first quantify fluid loss induced by dehydration with multicomponent T2 relaxometry using a standard MRI. We then extend these findings and demonstrate a portable, low-field MR sensor exhibits comparable performance via a similar measurement while offering significantly reduced sensor mass, measurement time, and system complexity.

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