Abstract #0283

Pre-surgical evaluation of residual cancer by breast MRI after neoadjuvant systemic treatment: DWI-based algorism

Rie Ota¹, Masako Kataoka¹, Maya Honda¹, Shotaro Kanao², Mami Iima¹, Kanae Miyake Kawai¹, Akane Ohashi¹, Ayami Ohno Kishimoto¹, Takaki Sakurai³, Tatsuki R Kataoka³, Masakazu Toi⁴, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University graduate school of medicine, Kyoto, Japan, ²Kobe City Medical Center General Hospital, Kobe, Japan, ³Department of Pathology, Kyoto University Hospital, Kyoto, Japan, ⁴Department of Breast Surgery, Kyoto University Hospital, Kyoto, Japan

We aimed to re-evaluate DWI of pre-surgical MRI as a clue to diagnose pCR or non-pCR. DCE-MRI including kinetic information were also evaluated for comparison. DWI-based evaluation of residual disease in pre-surgical MRI demonstrate excellent diagnostic performance. On the other hand, residual disease is difficult to evaluate based on kinetic information. DWI-based evaluation of residual disease is a useful approach in pre-surgical evaluation of breast cancer following neoadjuvant systemic treatment.

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