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Abstract #0325

Concurrent mapping of electric currents and neurophysiological changes during Transcranial Direct Current Stimulation (tDCS)

Mayank Jog1,2, Kay Jann1, Lirong Yan1, and Danny JJ Wang1

1USC Stevens Neuroimaging and Informatics Institute, Los Angeles, CA, United States, 2UCLA Neurology, Los Angeles, CA, United States

Transcranial Direct Current Stimulation(tDCS) is a non-invasive neuromodulation technique that uses milliampere currents (applied at the scalp) to modulate cortical excitability. Although tDCS has been shown to improve clinical symptoms in depression, stroke rehabilitation and pain, the exact mechanism of tDCS is not yet fully understood. To help advance the study of tDCS mechanisms, we developed a novel technique that, for the first time, enables concurrent mapping of (i) the applied electric current and (ii) the neurophysiological changes induced in-vivo. In this work, we demonstrate the feasibility as well as reliability of this novel technique through phantom and in-vivo experiments.

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