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Abstract #0352

Fast High-Resolution Diffusion Tensor Imaging of the Cervical Spinal Cord Using Point-Spread-Function Encoded EPI (PSF-EPI)

Sisi Li1, Yishi Wang1,2, Yong Hai3, Hanwen Zhang4, and Hua Guo1

1Department of Biomedical Engineering, Center for Biomedical Imaging Research, Beijing, China, 2Philips Healthcare, Beijing, China, 3Beijing Chao Yang Hospital, Beijing, China, 4Beijing ChaoYang Hospital, Beijing, China

Diffusion tensor imaging (DTI) of spinal cord holds great promise to aid diagnosis of spine-related diseases. However, it is greatly limited in clinics by the physiological motion induced artifacts and susceptibility inhomogeneity induced distortions. To reduce distortions in DTI, various multi-shot EPI (MS-EPI) methods have been proposed. However, the acquisition time is prolonged due to multiple shots. In this study, we achieved cervical spine DTI using only 6 shots based on a distortion- and blurring- free MS-EPI technique, Point-Spread-Function Encoded EPI (PSF-EPI). The acquisition time is within 5 minutes. The efficacy of PSF-EPI is demonstrated on healthy volunteers and patients.

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