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Abstract #0385

Early identification of neonatal mild hypoxic-ischemic encephalopathy by Amide Proton Transfer magnetic resonance imaging: A Pilot Study

Sijin Chen1, Yingjie Mei2, and Yikai Xu1

1Medical Image Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2Philips Healthcare, Guangzhou, China

Neonatal hypoxic-ischemic encephalopathy (HIE) is a major complication of perinatal asphyxia, with high morbidity and morbidity. APT imaging is a potential technique for detecting in vivo characterization of the internal environment during hypoxic-ischemic brain injury. We investigated the feasibility of APT in differentiating neonatal mild HIE from normal age-matched infants, and to explore the changes in the internal environment in neonatal mild HIE. The results indicate that APT imaging for neonatal mild HIE is a useful and feasible technique with diagnostic capability.

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