Meeting Banner
Abstract #0387

A MR-based nomogram for predicting cerebral palsy in periventricular leukomalacia children before 2 years old

Tingting Huang1,2, Zhe Liu1, Chao Jin1, Haoxiang Jiang1,3, Heng Liu1, Wei Xing2, Yunhu Wu2, Xiaocheng Wei4, Gang Zhang2, and Jian Yang1

1The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China, 2The First Affiliated Hospital of Henan University of traditional Chinese Medicine, Zhengzhou, China, 3Xi’an Children Hospital, Xi'an, China, 4GE Healthcare, Bei Jing, China

Early identification of cerebral palsy (CP) in children with periventricular leukomalacia (PVL) is crucial for prescribing the indispensable treatment and rehabilitation. In this study, we visually assessed PVL-associated MR signs, i.e. T2/T2 Flair hyperintense in the centrum ovale, posterior limb of internal capsule, pedunculus cerebri and thalamus, and found they were independent predictors of CP. Based on these signs, a MR-based nomogram for predicting CP in PVL children aged less than 2 yr was developed. Results indicated that the area under receiver operating characteristic curve, sensitivity and specificity for this nomogram were 0.921, 91.2% and 83.3%, respectively. These suggested the potential role of our MR nomogram in predicting the CP outcome of PVL children before 2 years old.

This abstract and the presentation materials are available to members only; a login is required.

Join Here