Early identification of cerebral palsy (CP) in children with periventricular leukomalacia (PVL) is crucial for prescribing the indispensable treatment and rehabilitation. In this study, we visually assessed PVL-associated MR signs, i.e. T2/T2 Flair hyperintense in the centrum ovale, posterior limb of internal capsule, pedunculus cerebri and thalamus, and found they were independent predictors of CP. Based on these signs, a MR-based nomogram for predicting CP in PVL children aged less than 2 yr was developed. Results indicated that the area under receiver operating characteristic curve, sensitivity and specificity for this nomogram were 0.921, 91.2% and 83.3%, respectively. These suggested the potential role of our MR nomogram in predicting the CP outcome of PVL children before 2 years old.