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Abstract #0459

Fat-free free-running coronary MRA at 1.5T using LIBRE water excitation pulses

Nemanja Masala1, Jessica A.M. Bastiaansen1, Lorenzo Di Sopra1, Davide Piccini1,2,3, Jérôme Yerly1,4, Roberto Colotti1, and Matthias Stuber1,4

1Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 3LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Previously published work in fully self-gated free-breathing 3D radial coronary MRA at 1.5T with cardiac-and-respiratory-motion-resolved reconstruction (Free-running framework) suffered from the disadvantage of requiring interrupted bSSFP with ramp-up and fat saturation pre-pulses. Using numerical simulations, in vitro and in vivo scans, we successfully tested the hypothesis that LIBRE, a new water excitation technique, obviates the need for such pre-pulses, improves time efficiency when compared to earlier approaches, and provides both superior fat saturation and vessel delineation relative to more conventional water excitation.

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