Abstract #0459

Fat-free free-running coronary MRA at 1.5T using LIBRE water excitation pulses

Nemanja Masala¹, Jessica A.M. Bastiaansen¹, Lorenzo Di Sopra¹, Davide Piccini^1,2,3, Jérôme Yerly^1,4, Roberto Colotti¹, and Matthias Stuber^1,4

¹Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ³LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁴Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Previously published work in fully self-gated free-breathing 3D radial coronary MRA at 1.5T with cardiac-and-respiratory-motion-resolved reconstruction (Free-running framework) suffered from the disadvantage of requiring interrupted bSSFP with ramp-up and fat saturation pre-pulses. Using numerical simulations, in vitro and in vivo scans, we successfully tested the hypothesis that LIBRE, a new water excitation technique, obviates the need for such pre-pulses, improves time efficiency when compared to earlier approaches, and provides both superior fat saturation and vessel delineation relative to more conventional water excitation.

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