Abstract #0480

First assessment of cardiac energy metabolism in the lateral and inferior segments of the left ventricle in vivo at 7T

Ladislav Valkovic^1,2, Jane Ellis¹, Lucian AB Purvis¹, Albrecht Ingo Schmid^1,3, Stefan Neubauer¹, and Christopher T Rodgers^1,4

¹OCMR, RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom, ²Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia, ³High-Field MR Centre, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ⁴The Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom

Using a novel whole-body transmit coil with an integrated 30-element receive array, powered by a 35kW RF power amplifier, we show the feasibility of whole-heart cardiac ³¹P-MRS at 7T. PSF simulations were performed to directly compare the new coil to a published protocol using a 16-element surface coil. The whole-body coil delivers analysable spectra from all left ventricular segments in the hearts of 3 volunteers, whereas the 16-element surface coil allowed probing energetics only in the proximal half of the left ventricle. This coil will enable new studies of focal disease and improve the SNR for regionally homogenous disease investigations.

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