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Abstract #0568

Development of 1H/13C RF Head Coil for Hyperpolarized 13C Imaging of Human Brain

Junjie Ma1, Ralph S. Hashoian2, Chenhao Sun3, Steve M. Wright3, Alexander Ivanishev4, Robert E. Lenkinski4, Craig R. Malloy1,5, Albert P. Chen6, and Jae Mo Park1,4,7

1Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, 2Clinical MR Solutions, Brookfield, WI, United States, 3Electrical and Computer Engineering, Texas A&M University, College Station, TX, United States, 4Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 5Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, 6GE Healthcare, Toronto, ON, Canada, 7Electrical Engineering, UT Dallas, Richardson, TX, United States

A customized 1H/13C RF head coil that consists of a 1H quadrature transmit (Tx) and receive (Rx) coil and 13C quadrature transmit and array receive (QTAR) coils was developed. The performance of the new head coil was evaluated using phantoms and compared to the existing 13C-only quadrature Tx/Rx (QTR) head coil. Metabolic imaging of human brain was performed using the 1H/13C head coil, following an injection of hyperpolarized [1-13C]pyruvate.

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