The goal is to compare DCE-MRI PK parameters with IVIM-MRI parameters and ADC in breast cancer diagnostic accuracy, and assess if integration of DCE and IVIM markers further improves diagnostic performance. Twenty-two patients with 23 suspicious breast lesions underwent pre-biopsy DCE- and DW-MRI with 12 b values. PK parameters were estimated using the Shutter-Speed model. IVIM parameters and ADC were derived with biexponential and monoexponential modeling of the DW-MRI data, respectively. Both DCE- and IVIM-MRI, with individual or combined markers, outperformed clinical MRI reading in breast cancer diagnosis. The integration of DCE and IVIM markers provided the best diagnostic performance.
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