Abstract #0604

Multi-shot DWI with multiplexed sensitivity encoding (MUSE) versus single-shot DWI in the breast

Yuxin Hu¹, Arnaud Guidon², Lloyd Estkowski³, Bruce Daniel^4,5, Brian Hargreaves^1,4,5, and Catherine Moran⁴

¹Department of Electrical Engineering, Stanford University, Stanford, CA, United States, ²Global MR Application and Workflow, GE Healthcare, Boston, MA, United States, ³Global MR Application and Workflow, GE Healthcare, Menlo Park, CA, United States, ⁴Department of Radiology, Stanford University, Stanford, CA, United States, ⁵Department of Bioengineering, Stanford University, Stanford, CA, United States

Diffusion-weighted imaging (DWI) has shown strong potential for clinical impact in breast MRI but is limited by low resolution and image distortion. Multi-shot acquisitions can help to address these limitations. Here we assess a multi-shot diffusion acquisition utilizing two different reconstructions in comparison to single-shot DWI in breast cancer patients. The assessment includes quantified perceived resolution and ratings of qualitative image characteristics with respect to the DCE-MRI acquisition.

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