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Abstract #0685

High Resolution Perfusion Imaging using Golden Angle Radial Arterial Spin Labelling

Thomas W Okell1 and Mark Chiew1

1WIN, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

Arterial spin labeling perfusion imaging at clinical field strengths is generally confined to relatively coarse voxels (~4 mm), preventing the investigation of perfusion variations on small spatial scales and leading to problems with partial volume effects. In this work we demonstrate the ability of a golden angle radial approach combined with a regularized reconstruction technique to produce time-resolved perfusion images with isotropic voxel sizes lower than 2 mm. This was shown to improve grey matter definition and reduce partial volume effects.

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