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Abstract #0753

Accuracy of real-time quantitative flow imaging in small diameters using compressed sensing at 7T: a phantom study

Johannes Töger1, Mads Andersen2, and Karin Markenroth Bloch3

1Department of Clinical Sciences, Diagnostic Radiology, Lund University, Lund, Sweden, 2Philips Healthcare, Copenhagen, Denmark, 3Lund University Bioimaging Center, Lund University, Lund, Sweden

Recent studies have shown that cerebrospinal fluid (CSF) flow is strongly affected by respiration, which may potentially be used for future diagnosis and treatment follow-up in diseases such as normal pressure hydrocephalus and congenital malformations. However, quantitative measurements of respiratory effects on CSF flow in small diameters are not currently available. Therefore, this abstract shows a phantom validation of flow measurement using a radial golden-angle real-time flow sequence, reconstructed using compressed sensing. Results show that mean velocities can be quantified with a small underestimation, suggesting that the protocol is promising for future study of respiratory effects on CSF flow.

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