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Abstract #0785

Fully Self-Gated Cardiac and Respiratory Motion-Resolved Isotropic 5D T1 Mapping of the Heart: Preliminary Results

Lorenzo Di Sopra1, Christopher W. Roy1, Jessica A.M. Bastiaansen1, Jérôme Yerly1,2, Davide Piccini1,3,4, Lionel Pierre Arn1, Matthias Stuber1,2, and Ruud B. van Heeswijk1,2

1Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 3Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 4LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

Current solutions for T1 mapping rely on 2D images of the heart, and require time-inefficient cardiac gating as well as long breath-holds. To address these drawbacks, a Free-running framework for fully self-gated cardiac and respiratory motion-resolved 5D imaging of the heart was extended to include T1 recovery contrast as a 6th dimension. The framework was tested at 3T in an ISMRM-NIST phantom and demonstrated good agreement between the estimated T1 values and reference standard. Preliminary 3D T1 maps in 3 healthy volunteers showed good resolution of the physiological motion and accurate T1 values of the myocardium and blood.

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