Abstract #0785

Fully Self-Gated Cardiac and Respiratory Motion-Resolved Isotropic 5D T1 Mapping of the Heart: Preliminary Results

Lorenzo Di Sopra¹, Christopher W. Roy¹, Jessica A.M. Bastiaansen¹, Jérôme Yerly^1,2, Davide Piccini^1,3,4, Lionel Pierre Arn¹, Matthias Stuber^1,2, and Ruud B. van Heeswijk^1,2

¹Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, ³Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ⁴LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

Current solutions for T1 mapping rely on 2D images of the heart, and require time-inefficient cardiac gating as well as long breath-holds. To address these drawbacks, a Free-running framework for fully self-gated cardiac and respiratory motion-resolved 5D imaging of the heart was extended to include T1 recovery contrast as a 6^th dimension. The framework was tested at 3T in an ISMRM-NIST phantom and demonstrated good agreement between the estimated T1 values and reference standard. Preliminary 3D T1 maps in 3 healthy volunteers showed good resolution of the physiological motion and accurate T1 values of the myocardium and blood.

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