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Abstract #0813

Parameter Encoding Efficiency in Transient and Steady-State Quantitative MRI Methods

David Leitão1, Joseph V. Hajnal1,2, Rui P. A. G. Teixeira1, and Shaihan Malik1

1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

This work proposes a neutral measure of encoding efficiency per square-root of time excluding any effects of image reconstruction from the analysis in order to compare spoiled gradient-echo based Magnetic Resonance Fingerprinting and steady-state methods for $$$T_1$$$ and $$$T_2$$$ estimation. The results obtained indicate that gradient spoiled Fingerprinting is up to $$$50\%$$$ more efficient per square-root-time than steady-state methods. The optimal sequences of pulses found have striking features with different duration fingerprint strategies having highest efficiency under different boundary conditions.

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