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Abstract #0833

A Cascaded Residual UNET for Fully Automated Segmentation of prostate and peripheral zone in T2-weighted 3D Fast Spin Echo Images

Lavanya Umapathy1, Wyatt Unger2, Faryal Shareef2, Hina Arif2, Diego Martin2, Maria Altbach2, and Ali Bilgin1,3

1Electrical and Computer Engineering, University of Arizona, Tucson, AZ, United States, 2Department of Medical Imaging, University of Arizona, Tucson, AZ, United States, 3Biomedical Engineering, University of Arizona, Tucson, AZ, United States

Multi-parametric MR images have been shown to be effective in the non-invasive diagnosis of prostate cancer. Automated segmentation of the prostate eliminates the need for manual annotation by a radiologist which is time consuming. This improves efficiency in the extraction of imaging features for the characterization of prostate tissues. In this work, we propose a fully automated cascaded deep learning architecture with residual blocks (Cascaded MRes-UNET) for segmentation of the prostate gland and the peripheral zone in one pass through the network. The network yields high dice scores (mean=0.91) with manual annotations from an experienced radiologist. The average difference in volume estimation is around 6% in the prostate and 3% in the peripheral zone.

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