We present the MESMERISED sequence which super-accelerates 7T STEAM imaging by employing both echo-shifting and multiband/simultaneous multislice acceleration. This leads to very high multiplicative acceleration factors and time efficiency for T1w and diffusion imaging. We illustrate this with 8x to 48x accelerated T1 relaxometry data at 1.5mm isotropic and 12x accelerated 3-shell diffusion data up to b = 5000s/mm2 at 1.7mm isotropic. MESMERISED extends possibilities to efficiently probe combined T1, T2 and diffusion contrast for multi-component modeling of relaxometry, diffusion and exchange.
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