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Abstract #0988

Preliminary application of Three-Dimensional Multifrequency MR Elastography for the Prostate Disease

Tianhui Zhang1, Ying Deng1, Sichi Kuang1, Bingjun He1, Jingbiao Chen1, Bing Wu2, Phillip Rossman3, Kevin J Glaser3, Sudhakar K Venkatesh3, Richard L Ehman3, and Jin Wang1

1Department of Radiology, The third affiliated hospital of Sun Yat-sen University, Guangzhou, China, 2MR Research China, GE Healthcare, Beijing, China, 3Department of Radiology, Mayo Clinic, Rochester, Armenia

Prostate cancer (PCa) is the second leading cause of cancer deaths among males in the in the United States. Early detection of clinically significant PCa is a major challenge. MR elastography (MRE) is a noninvasive technique capable of quantifying the mechanical properties of tissue and has shown promising results in the detection and localization of PCa. Our results show that transpelvic three-dimensional (3D) MRE using a pelvic wall driver could be successful performed in the prostate at the frequencies of 60 Hz and 90 Hz and can provide a potential quantitative biomarker to evaluate prostate diseases.

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