Abstract #1003

Whole lesion IVIM analysis in the diagnosis of thyroid tumor: Comparison with Conventional Diffusion-Weighted Imaging

Yunlong Yue¹, Minghui Song¹, Yanfang Jin¹, Jinsong Guo¹, Lili Zuo¹, Queenie Chan², and Zhenchang Wang³

¹MR Department, Beijing Shijitan Hospital of Capital Medical University, Beijing, China, ²Philips Healthcare, Hong Kong, China, ³Beijing Friendship Hospital, Capital Medical University, Beijing, China

To compare the diagnostic efficiency of IVIM parameters and conventional DWI (b=600 and b=990) derived from 3D whole-lesion (W-L ROI) delineation. Forty-three patients with 46 pathologically confirmed thyroid nodules were involved. According to ROC curve, D, f, ADC₆₀₀ and ADC₉₉₀ values showed diagnostic significance with the AUC values of 0.962, 0.756, 0.970 and 0.939 respectively. Furthermore, the Youden index of D value (0.871) was higher than that of ADC₆₀₀ (0.826). IVIM is a more promising tool in the differentiation of benign and malignant thyroid nodules using W-L ROI delineation than conventional DWI.

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