Abstract #1006

Exploring diffusion properties in neocortical grey matter using inversion recovery diffusion weighted imaging

Fakhereh Movahedian Attar^1,2, Bibek Dhital^1,3,4, Luke J Edwards¹, and Nikolaus Weiskopf^1,5

¹Neurophysics, Max Planck Institute for Human cognitive and Brain Sciences, Leipzig, Germany, ²International Max Planck Research School on Neuroscience of Communication: Function, Structure, and Plasticity, Leipzig, Germany, ³Medical Center, Faculty of Medicine, University Freiburg, Freiburg, Germany, ⁴Department of Medical Physics, University Freiburg, Freiburg, Germany, ⁵Felix Bloch Institute for Solid State Physics, Faculty of Physics and Earth Sciences, Leipzig University, Leipzig, Germany

We measured inversion recovery prepared diffusion signal for grey matter. We found that the mean diffusivity (MD) in grey matter drops significantly for TIs higher than the nulling TI. MD in GM dropped from around 0.8×10^-3 mm²/s before the null point to around 0.6×10^-3 mm²/s immediately after the null point. Our findings suggest that the neocortical gray matter could be characterized using a two dimensional T1-diffusion correlation measurement.

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