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Abstract #1024

Feasibility of Rapid Automated Liver Quantitative Susceptibility Mapping in a Patient Population

Ramin Jafari1, Sujit Sheth2, Pascal Spincemaille2, Thanh D. Nguyen2, Martin R. Prince2, Yan Wen1, Yihao Guo3, Kofi Deh2, Zhe Liu1, Daniel Margolis2, Gary M. Brittenham4, Andrea S. Kierans2, and Yi Wang1

1Cornell University, New York, NY, United States, 2Weill Cornell Medicine, New York, NY, United States, 3Southern Medical University, Guangzhou, China, 4Columbia University Medical Center, New York, NY, United States

Accurate measurement of the liver iron concentration (LIC) is needed to guide iron-chelating therapy for patients with transfusional iron overload. In this work, we investigate the feasibility of automated quantitative susceptibility mapping (QSM) to measure the LIC in clinical practice. We propose to incorporate In-phase echo acquisition for rapid, robust initialization of the field in water-fat separation problem (T2*-IDEAL).

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