Abstract #1024

Feasibility of Rapid Automated Liver Quantitative Susceptibility Mapping in a Patient Population

Ramin Jafari¹, Sujit Sheth², Pascal Spincemaille², Thanh D. Nguyen², Martin R. Prince², Yan Wen¹, Yihao Guo³, Kofi Deh², Zhe Liu¹, Daniel Margolis², Gary M. Brittenham⁴, Andrea S. Kierans², and Yi Wang¹

¹Cornell University, New York, NY, United States, ²Weill Cornell Medicine, New York, NY, United States, ³Southern Medical University, Guangzhou, China, ⁴Columbia University Medical Center, New York, NY, United States

Accurate measurement of the liver iron concentration (LIC) is needed to guide iron-chelating therapy for patients with transfusional iron overload. In this work, we investigate the feasibility of automated quantitative susceptibility mapping (QSM) to measure the LIC in clinical practice. We propose to incorporate In-phase echo acquisition for rapid, robust initialization of the field in water-fat separation problem (T2*-IDEAL).

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