Abstract #1040

STrategically Acquired Gradient Echo (STAGE) Imaging for Standardized Multi-Contrast and Quantitative Brain Data Acquisition: Validating T1 mapping and Preliminary Clinical Results

Yongsheng Chen^1,2, M. Marcella Lagana³, Shuang Xia⁴, and E. Mark Haacke^1,2

¹Department of Radiology, Wayne State University, Detroit, MI, United States, ²The MRI Institute for Biomedical Research, Bingham Farms, MI, United States, ³IRCCS, Fondazione Don Carlo Gnocchi ONLUS, Milano, Italy, ⁴Tianjin First Central Hospital, Tianjin, China

One major thrust in radiology today is imaging standardization with rapidly acquired quantitative multi-contrast information. This is critical for multi-center trials, for the collection of big data and the use of artificial intelligence in evaluating the data. STAGE is one such method that can provide more than ten qualitative and quantitative pieces of information in roughly 5 minutes or less at 3T. In this work, we introduce several new image contrasts derived from STAGE and validate STAGE T1 mapping using the ISMRM/NIST phantom as well as in vivo data. We also present some preliminary pathological results.

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