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Abstract #1061

Double-Shot Semi-Adiabatic Localization for Ultra Short Echo Time Magnetic Resonance Spectroscopy

Karl Landheer1, Michael Garwood2, Ralph Noeske3, and Christoph Juchem1,4

1Biomedical Engineering, Columbia University, New York, NY, United States, 2Center for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 3GE Healthcare, Berlin, Germany, 4Radiology, Columbia University, New York, NY, United States

Modern magnetic resonance spectroscopic (MRS) pulse sequences which employ localization through adiabatic pulses suffer from long minimum echo times ($$$\ge$$$ 19 ms). Here we developed a novel MRS pulse sequence which allows for an echo time of 8 ms with adiabatic localization in two of the three spatial dimensions, at the cost of two-shot volume localization. The sequence is highly robust to B1 inhomogeneity and does not have any anomalous J-modulation since no slice-selective refocusing pulses are used. High spectral quality was obtained in phantom experiments, although strong lipid contamination was observed, consistent with previously reported two-shot localization methods.

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