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Abstract #1067

Functional Magnetic Resonance Spectroscopy in the mouse brain

Clémence Ligneul1, Julia M Huntenburg1, Francisca Fernandes1, and Noam Shemesh1

1Champalimaud Neuroscience Programme, Champalimaud Centre for the Unknown, Lisbon PT, Portugal

Functional magnetic resonance spectroscopy (fMRS) can provide insights on brain metabolism under activation, as has already been shown in humans. Assessing fMRS in mice would open interesting perspectives for understanding neural activity given mouse transgenics. We report preliminary encouraging results of fMRS in the mouse superior colliculus, during visual stimulation at 9.4 T (using a cryocoil for reception). Time courses of different metabolites concentrations notably reveal metabolite signal modulations during activation.

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