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Abstract #1196

Feasibility of brain pathology assessment with diffusion imaging on a portable scanner using a fixed encoding field

Jason Stockmann1,2, Patrick McDaniel3, Christopher Vuahgn4, Clarissa Z. Cooley2,4, and Lawrence Wald4,5

1A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 4A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 02129, MA, United States, 5Harvard Medical School, Cambridge, MA, United States

Diffusion-weighted MRI is widely used for diagnosing brain pathology, but is typically not available close to the site of acute brain injury due to size, weight, power, and exclusion-zone constraints. Recently-developed lightweight brain scanners have achieved portability by using inhomogeneous B0 fields and by correcting for field imperfections during image reconstruction. Building on work done by the petroleum industry with single-sided borehole magnets, we use the built-in spatial encoding field of a portable brain scanner for both diffusion-encoding and spatial-encoding. We also introduce a method for using dummy refocusing pulses to vary the b-value without changing TEeff and T2-contrast.

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