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Abstract #1218

Click Your Fat Away: Rapid Synthetic Knee MR Imaging with Switchable Fat and Magnetization-Transfer Contrast

Tom Hilbert1,2,3, Jan Fritz4, Patrick Omoumi2, José P. Marques5, Emilie Mussard1,2,3, Jean-Philippe Thiran2,3, Reto Meuli2, and Tobias Kober1,2,3

1Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 2Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, 3LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 4Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 5Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Synthetic MRI is increasingly used in clinical practice to supplement or replace conventional MRI, due to the ability to generate both a multitude of MR images with weighted contrasts and quantitative T1, PD and T2 maps, which is of high interest in musculoskeletal imaging. To further broaden the application of synthetic image contrasts, we developed a method which allows switching between images with and without fat signal as well as magnetization-transfer weighting. The method includes three pulse sequences to estimate quantitative maps for the calculation of a variety of contrasts and requires a total acquisition time of 6:46 min.

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