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Abstract #1244

MRI-based radiomics nomogram in differentiating sinonasal mucosal melanoma from sinonasal lymphoma

Linying Guo1, Zuohua Tang1, Yang Song2, Guang Yang2, Jing Zhang2, Yucheng Pan1, zebin xiao1, and Zhongshuai Zhang3

1EENT Hospital of Fudan University, Shanghai, China, 2East China Normal University, Shanghai, China, 3SIEMENS Healthcare, Diagnostic Imaging, Shanghai, China

Differentiating sinonasal mucosal melanoma (SNMM) from sinonasal lymphoma before surgery is important. However, it is a challenge to perform preoperative diagnosis through either histological biopsy or conventional MRI. In this study, an MRI-based individualized 3D nomogram through radiomics was constructed, and its value was explored in the differentiation between the two entities. The nomogram shows satisfactory efficiency in the diagnosis, and its performance was better than that of human radiologists. This study demonstrates that noninvasive MRI-based radiomics could be helpful in the preoperative differentiation of SNMM from sinonasal lymphoma.

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