Proton density fat fraction (PDFF) measurements can quantify oedema and fat metaplasia in patients with spondyloarthritis. The reproducibility of PDFF measurement in the bone marrow of the sacroiliac joint was assessed in volunteers on 3 systems from different manufacturers, using a range of specialist and base-level product protocols. PDFF measurements on different platforms correlate well, but there is also a bias between the base-level and advanced methods. Performing an offline reconstruction with a multi-peak fat model and a T2* correction term reduces this bias.
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