Abstract #1288

Comparison of Quantitative MRI Fat-Fraction measurement in SIJ joint on different scanner platforms

Alan Bainbridge¹, Timothy J Bray², Naomi Sakai², Sarah Tansley³, Nicola Fulstow³, Raj Sengupta³, and Margaret A Hall-Craggs²

¹Medical Physics and Biomedical Engineering, University College London Hospitals, London, United Kingdom, ²Centre for Medical Imaging, University College London, London, United Kingdom, ³Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom

Proton density fat fraction (PDFF) measurements can quantify oedema and fat metaplasia in patients with spondyloarthritis. The reproducibility of PDFF measurement in the bone marrow of the sacroiliac joint was assessed in volunteers on 3 systems from different manufacturers, using a range of specialist and base-level product protocols. PDFF measurements on different platforms correlate well, but there is also a bias between the base-level and advanced methods. Performing an offline reconstruction with a multi-peak fat model and a T2* correction term reduces this bias.

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