Perfusion imaging of epiphyseal bone marrow in the distal femoral condyle can provide valuable insights into the pathophysiological mechanism of knee injuries or diseases, and has a great potential to facilitate the management of developmental knee diseases. A previous study at 3T indicated that low perfusion signal-to-noise ratio (SNR) imposed a great challenge to achieve high-quality bone marrow arterial spin labeling (ASL) images. 7T can benefit ASL imaging due to greatly increased blood T1 and imaging SNR. The presented study evaluated the feasibility and challenges of epiphyseal bone marrow ASL imaging in the distal femur at 7T.
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