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Abstract #1339

Fatty infiltration of paraspinal muscles is associated with bone mineral density of lumbar spine

xiaodong zhang1, Yinxia Zhao1, Mingqian Huang2, Shaolin Li3, and Chuan Huang2

1The Third Affiliated Hospital of Southern Medical University (Orthopaedic Hospital of Guangdong Province), guangzhou, China, 2Stony Brook Medicine, Stony Brook, NY, United States, NY, NY, United States, 3The Fifth Affiliated Hospital of Sun Yet-sen Univeristy, zhuhai, China

Paraspinal muscle fatty infiltration (FI) is an important factor affecting spinal function. However, there is no previous study investigating the relationship between paraspinal muscle FF and spinal BMD. Our study demonstrated that fat fractions of erector spinae (ES), multifidus(MF) and psoas(PS) of subjects with normal bone density were all significantly less than those of subjects with osteopenia and those with osteoporosis. There is an inverse correlation between paraspinal muscle FF and vertebral BMD after controlling for age, sex and BMI. Our results show paraspinal muscle FI increases while vertebral BMD decreases.

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