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Abstract #1353

High resolution assessment of intramuscular fat content in the calf using T2-weighted MRI

Xiaowan Li1, Conlin C Christopher1, Christopher Hanrahan1, Vivian S Lee2, and Jeff Lei Zhang1

1Department of Radiology and Imaging Sciences, University of Utah School of Medicine, Salt Lake City, UT, United States, 2Verily Life Sciences, Cambridge, MA, United States

Intramuscular fat is an important indicator of the health of the lower extremities. It can be difficult with conventional Dixon techniques to acquire high resolution fat-fraction maps, which may be helpful for detailed analysis of the muscle tissue. We propose to use a linear model to generate a high resolution fat-fraction map from high resolution T2-weighted images. The results show that the proposed method and the conventional Dixon method have good agreement. The high resolution fat fraction maps generated with the proposed method reveal anatomic details of intramuscular fat not visible with the conventional method.

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