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Abstract #1389

Quantification of Non-calcified and Calcified Zones in Articular Cartilage using MRI and PLM at Microscopic Resolution

Farid Badar1 and Yang Xia1

1Physics, Oakland University, Rochester Hills, MI, United States

The zone of calcified cartilage is the least explored region of cartilage in MRI, due to a strong dipolar interaction and a high mineralization of the subchondral region in articular cartilage. T2 weighted images by standard SE and GE sequences show little intensity of ZCC, whereas T2 and T1 weighted at the magic angle can highlight some parts of the region. Quantitative UTE can measure T2 of ZCC down to a fraction of a millisecond. With the aid of PLM, we can correlate the quantitative ┬ÁMRI data with the optical properties of the ZCC.

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