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Abstract #1410

Imaging of the Region of the Osteochondral Junction (OCJ) Using a 3D Adiabatic Inversion Recovery Prepared Ultrashort Echo Time Cones (3D IR-UTE Cones) Sequence at 3T

Ya-Jun Ma1, Saeed Jerban1, Michael Carl2, Lidi Wan1, Tan Guo1, Hyungseok Jang1, Graeme Bydder 1, Eric Chang1,3, and Jiang Du1

1Radiology, University of California, San Diego, San Diego, CA, United States, 2GE health care, San Diego, CA, United States, 3VA San Diego Healthcare System, San Diego, CA, United States

The osteochondral junction (OCJ) region serves as a functional barrier between the synovial joint space and subchondral bone marrow, and may play an important role in the pathogenesis of osteoarthritis (OA). MRI of the OCJ region is difficult due to the short T2 of deep radial uncalcified cartilage and calcified cartilage, which results in little or no signal when conventional pulse sequences are used. The purpose of this study was to use a 3D adiabatic inversion recovery prepared UTE Cones (3D IR-UTE-Cones) sequence for volumetric imaging of OCJ region with high spatial resolution and contrast in clinically acceptable scan times.

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