Abstract #1426

Visualization and quantification of epiphyseal cartilage vasculature using quantitative susceptibility maps of pediatric knee specimens

Kai D. Ludwig^1,2, John Strupp^1,2, Casey P. Johnson^1,2, Stefan Zbyn^1,2, Mikko J. Nissi^1,2,3, Ferenc Tóth⁴, Kevin Shea⁵, Cathy S. Carlson⁶, and Jutta M. Ellermann^1,2

¹Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, United States, ²Radiology, University of Minnesota, Minneapolis, MN, United States, ³Applied Physics, University of Eastern Finland, Kuopio, Finland, ⁴Veterinary Population Medicine, University of Minnesota, St. Paul, MN, United States, ⁵Orthopaedic Surgery, Stanford University, Stanford, CA, United States, ⁶Veterinary Clinical Sciences, University of Minnesota, St. Paul, MN, United States

Visualization of the vasculature within the epiphyseal cartilage of the distal femur of the skeletally immature knee joint is possible with susceptibility-weighted MRI. A post-processing pipeline is described to segment and quantify the vascular density within two distinct vascular beds of the distal femoral epiphyseal cartilage using quantitative susceptibility maps. The described post-processing may allow identification of vascular abnormalities at early stages of development and also may improve assessment of therapeutic interventions.

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