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Abstract #1450

Calibrated Coil Combination for Fixed-Geometry, Low-Frequency Coils with Application to Hyperpolarized 13C Measurements

Juan Diego Sánchez Heredia1, Rie B. Hansen1, Rafael Baron1, Esben S. Szocska Hansen2, Daniel H. Johansen1, Vitaliy Zhurbenko1, Christoffer Laustsen2, Lars G. Hanson1, and Jan H. Ardenkjær-Larsen1

1Department of Electrical Engineering, Technical University of Denmark (DTU), Kgs. Lyngby, Denmark, 2MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

We explore a new design approach for low frequency RF coils, where a transmit and receive array are built together in a totally rigid frame, and therefore their B1+ and B1- distributions can be accurately mapped and used as prior information for SNR-optimal combination of signals from different coil elements. Using this principle, a coil is designed for 13C MRS of a pig at 3T (32.13 MHz). We show that at this frequency, the effect of sample loading is minimal, and the prior information obtained in phantoms benefits in-vivo experiments. This one-time calibration allows for optimal combination of coil signals, which is also expected to improve parallel imaging performance.

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