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Abstract #1591

3D Printed Mouse Brain Holders for High Throughput Ex Vivo MRI

Dong Kyu Kim1, Autumn R Greenfield1, and Mark D Does1,2,3

1Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 2Vanderbilt University Institute of Imaging Sciences, Vanderbilt University, Nashville, TN, United States, 3Department of Electrical Engineering, Vanderbilt University, Nashville, TN, United States

High throughput MRI of ex vivo mouse brains has been established as a powerful tool for studying mouse models of neurological disorders. These studies have used a RF coil array to image up to 16 mouse brains simultaneously; however, most pre-clinical MRI facilities are not equipped with multiple receivers and may not have a high field magnet with sufficient bore size to accommodate multiple coils. Here, we present designs for 3D-printed multiple mouse brain holders that can be produced inexpensively and enable high quality multiple mouse brain MRI with RF coils ≥ 25 mm diameter.

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