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Abstract #1595

A 3T MRI platform for imaging rodent models by integrating a dedicated high-strength gradient coil on a whole-body magnet

Sheng-Min Huang1,2, Kuan-Hung Cho1, Ming-Jye Chen1, Hsuan-Han Chiang1, Chang-Hoon Choi3, Richard Buschbeck3, Ezequiel Farrher3, N. Jon Shah3,4,5,6, Ruslan Garipov7, Ching-Ping Chang8, Hsu Chang1, and Li-Wei Kuo1,9

1Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan, 2Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, 3Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany, 4Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Jülich, Jülich, Germany, 5JARA - BRAIN - Translational Medicine, Aachen, Germany, 6Department of Neurology, RWTH Aachen University, Aachen, Germany, 7MR Solutions Ltd., Guildford, United Kingdom, 8Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan, 9Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan

In this study, a high-strength gradient coil dedicated for imaging rodent models has been successfully integrated on a whole-body 3T MRI magnet. The imaging capability of this system has been qualitatively and quantitatively demonstrated using phantom, ex-vivo specimen and in-vivo rat experiments. Since the hardware components used for integration on our system are independent from system vendors, this study can be a practically useful guide, especially for those who want to conduct small animal imaging on clinically used magnets.

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