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Abstract #1609

The Use of Relaxation Maps from Synthetic MRI in Differential Diagnosis of Prostate Cancer

Yadong Cui1,2, Yue Lin1,2, Chunmei Li1, Jianxun Qu3, Bing Wu3, and Min Chen1,2

1Department of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China, 2Graduate School of Peking Union Medical College, Beijing, China, 3GE Healthcare, Beijing, China

Synthetic MRI enables absolute quantification of T1, T2 and (proton density) PD value. The aim of the study was to primarily evaluate the feasibility of synthetic MRI in differential diagnosis of (prostate cancer) PCa. We analyzed 18 PCa lesions in 14 PCa patients, 26 SH (stromal hyperplasia), 25 GH (glandular hyperplasia) nodules and 21 prostatitis areas in 22 non-PCa patients who underwent multi-parameter MRI before needle biopsy. T1WI, T2WI, DWI and MAGiC (magnetic resonance image compilation) sequences were acquired respectively. Our results showed the T1 and T2 value of PCa lesion was significantly lower than GH nodule and prostatitis area. The PD value of PCa lesion was significantly lower than GH nodule. We concluded that synthetic MRI was helpful for differential diagnosis of PCa.

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