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Abstract #1639

Texture Analysis Comparison between MR and PET for Prostate Cancer MRI Guided Biopsy

Raisa Binte Rasul1, Joshua Cornman-Homonoff2, Sadek Nehmeh2, and Daniel Margolis2

1Biomedical Engineering, Cornell University, Ithaca, NY, United States, 2Radiology, Weill Cornell Medicine, New York City, NY, United States

PET scans can detect prostate lesions, locations in the prostate where biopsy could reveal about treatment strategy. PET has low resolution compared to MRI and doesn't show surrounding anatomy necessary for accessing the prostate. Texture feature maps in MRI might include information about lesion location. MRI prostate texture features maps were compared with superimposed PET scans. Preliminary data suggest correlation between PET intensity and PI-RADS score, and weak correlation between less texture and lesion location. Though low texture values might correlate with higher tumor recurrence risk and lead to improved MRI-guided biopsy, finding exact lesion location in MRI remains challenging.

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