Detection of Pancreatic Ductal Adenocarcinoma and Liver Metastases: Comparison of Contrast-enhanced MR Imaging with Ga-EOB-DTPA and Extracellular Contrast Materials

Ga-EOB-DTPA-enhanced MR imaging is well established imaging modality for the detection of liver metastases. On the other hand, it is expected that the arterial enhancement of solid organs is weaker comparing with extracellular contrast materials (ECCMs) because of its lower dosage. Our results demonstrated that the signal intensity ratio of the pancreas, tumor-to-pancreas contrast-to-noise ratio, and diagnostic performance for detecting pancreatic ductal adenocarcinoma (PDAC) were comparable, but the sensitivity for detecting liver metastases was better in Ga-EOB-DTPA compared with ECCMs, which suggests the usefulness of Ga-EOB-DTPA for evaluating patients with PDAC.