Chronic mesenteric ischemia (CMI) causes blood flow reduction in the intestines, often due to atherosclerosis. This study uses 4D flow MRI to quantify and compare pulsatility (PI) and resistivity indices (RI) in mesenteric vasculature in patients with a suspicion of CMI (N=19) and healthy individuals (N=20). PI and RI were measured in 9 mesenteric vessels before and after meal ingestion. In patients with CMI, aortic PI were significantly decreased both before and after a meal compared to controls, while postprandial SV and SMV PI values were significantly increased. RI values were not significantly different between groups.