Meeting Banner
Abstract #1674

A new MR-based Perianal Crohn’s disease activity score: Multicentre study

Ali Alyami1,2,3, Caroline Hoad1,3, Konstantinos Argyriou4, White Jonathan4, Uday Bannur5, Khalid Latief5, Christopher Clarke5, Phillip Lung6, Penny Gowland3, and Gordon Moran1,4

1Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, United Kingdom, 2Faculty of Applied Medical Sciences, Diagnostic Radiology, Jazan University, Jazan, Saudi Arabia, 3Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 4NIHR Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and University of Nottingham, University of Nottingham, Nottingham, United Kingdom, 5Radiology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom, 6Radiology, St Mark's Hospital and London North West Healthcare NHS Trust, London, United Kingdom

Perianal Crohn’s disease (pCD) is a potential complication in CD. Absence of reliable disease measures makes disease monitoring unreliable. MRI is an effective imaging method for the evaluation of patients with pCD. Quantitative MRI sequences, such as diffusion-weighted image (DWI), and magnetization transfer (MT) offer opportunities to improve diagnostic capability. The aim of this study was to measure disease activity within a pCD patient cohort using quantitative MRI sequences (DWI and MT), at different field strengths, before and after biological therapy. The study is ongoing with patients presenting with a range of clinical and inflammatory markers of disease activity.

This abstract and the presentation materials are available to members only; a login is required.

Join Here