Abstract #1678

Comparison of abdominal lymph nodes between healthy volunteers and patients with inflammatory gastrointestinal diseases.

Hannah G Williams¹, Caroline L Hoad¹, Robert Scott², Gordon Moran², Guruprasad P Aithal², Luca Marciani², and Penny A Gowland¹

¹Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, ²Nottingham Digestive Diseases Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom

Inflammatory diseases of the gastrointestinal tract are likely to cause enlargement of the abdominal lymph nodes which could potentially act as a biomarker of local inflammation. Lymphatics have been identified using a range of MRI sequences but previous work has largely focused on changes in cancer rather than chronic inflammatory diseases. We present here the first comparison of quantitative non-invasive MRI measures of T2, Apparent Diffusion Coefficient (ADC) and size of lymph nodes in healthy volunteers and patients with a range of inflammatory gastrointestinal diseases.

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