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Abstract #1683

Differential Diagnosis of Intrahepatic Mass-forming Cholangiocarcinoma and Solitary Hypovascular Hepatic Metastasis Using Whole-Tumor Texture Features Based on Apparent Diffusion Coefficient and Fractional Anisotropy Signal Intensity Maps

Ying Zhao1 and Ailian Liu1

1Department of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China

This work aimed for ADC and FA texture features based strategy to identify intrahepatic mass-forming cholangiocarcinoma (IMCC) and solitary hypovascular hepatic metastasis (SHHM) which may represent a diagnostic challenge due to many overlapping MRI features. The results showed that ADC and FA texture features can differentiate IMCC and SHHM. The Grey Level Non-uniformity (GLN) achieved the best result (AUC: 0.820; sensitivity: 79.2%; specificity: 86.2%) on ADC signal intensity map, forming a valuable strategy for clinical practice.

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