Abstract #1705

The Diagnostic Performance of LI-RADS version 2018 and the Value of Ancillary Features Favoring Hepatocellular Carcinoma (HCC) in the Diagnosis of 10-19 mm HCC on Extracellular Contrast-enhanced MRI.

Jingbiao Chen¹, Sichi Kuang¹, Bingjun He¹, Yao Zhang¹, Hao Yang¹, Ying Deng¹, Kathryn Fowler², Jin Wang¹, and Claude B. Sirlin²

¹Department of Radiology, The third affiliated hospital of Sun Yat-sen University, guangzhou, China, ²Department of Radiology, University of California at San Diego, La Jolla, CA, United States

Hepatocellular carcinoma (HCC) is the second most cause of cancer death worldwide. Early detection of small HCC can prolong patient survival. Recent updates have changed diagnostic criteria for LI-RADS v2018 for 10-19 mm HCC, and the impact on accuracy has not yet been studied. We found that LI-RADS v2018 provides 68.2% sensitivity, 91.7% specificity, and 71.8% accuracy for 10-19 mm HCC diagnosis in a Chinese population with chronic liver disease. Several modifications of LI-RADS were explored (e.g., pooling LR-4 and LR-5; allowing ancillary features favoring HCC to upgrade LR-4 to LR-5 and/or convert LR-M to LR-5), some sensitivities were mild improved without specificities increase.

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