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Abstract #1705

The Diagnostic Performance of LI-RADS version 2018 and the Value of Ancillary Features Favoring Hepatocellular Carcinoma (HCC) in the Diagnosis of 10-19 mm HCC on Extracellular Contrast-enhanced MRI.

Jingbiao Chen1, Sichi Kuang1, Bingjun He1, Yao Zhang1, Hao Yang1, Ying Deng1, Kathryn Fowler2, Jin Wang1, and Claude B. Sirlin2

1Department of Radiology, The third affiliated hospital of Sun Yat-sen University, guangzhou, China, 2Department of Radiology, University of California at San Diego, La Jolla, CA, United States

Hepatocellular carcinoma (HCC) is the second most cause of cancer death worldwide. Early detection of small HCC can prolong patient survival. Recent updates have changed diagnostic criteria for LI-RADS v2018 for 10-19 mm HCC, and the impact on accuracy has not yet been studied. We found that LI-RADS v2018 provides 68.2% sensitivity, 91.7% specificity, and 71.8% accuracy for 10-19 mm HCC diagnosis in a Chinese population with chronic liver disease. Several modifications of LI-RADS were explored (e.g., pooling LR-4 and LR-5; allowing ancillary features favoring HCC to upgrade LR-4 to LR-5 and/or convert LR-M to LR-5), some sensitivities were mild improved without specificities increase.

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