Texture analysis (TA) based on apparent diffusion coefficient (ADC), T1 and T2 mapping to evaluate glomerular filtration rate (GFR) has not been explored before. A total of 116 participants underwent DWI, T1 and T2 mapping of both kidneys on a 3T MR scanner and texture features were measured for the cortex and medulla of each kidney. Models incorporating texture features mainly quantified from ADC and T1 maps produced a satisfactory performance for detecting abnormal renal function and characterizing the different severity of GFR decline. It’s promising that TA based on ADC and T1 maps could serve as imaging markers to evaluate renal function.
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