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Abstract #1750

New MRI Method for the Detection of Liver Fibrosis: Validation and Staging

Jie Zheng1, Lichuan Yang2, Joseph Gabriel2, Guangzhong Wang2, Shaozhu Liu2, Tony Wang2, and Bob Zhang2

1Radiology, Washington University in St. Louis, Saint Louis, MO, United States, 2Kunming Biomed International, Kunming, China

The purpose of this study was to develop a MR imaging markers for quantitative assessment of liver fibrosis and validate the method. Both normal monkeys and monkeys with non-alcoholic steatohepatitis were used for the validation study compared to histopathology of liver biopsy specimens. Liver extracellular volume was quantified and correlated strongly with biopsy fibrosis scores.

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