Liver dysfunction impairs the uptake of gadobenate dimeglumine by liver parenchyma, which reduces hepatocellular carcinoma (HCC) conspicuity on hepatobiliary phase (HBP) images. Although the effect of Child-Pugh class and some biologic factors have been investigated, there is a paucity of data on other plausible predictors of HBP adequacy. Here we show that elevated albumin level, prolonged HBP delay time, and absence of liver cirrhosis predict HBP adequacy on gadobenate-MRI in patients with chronic liver disease and HCC. In the subset of patients with cirrhosis and HCC, adequate HBP was associated with elevated serum creatinine level and prolonged HBP delay time.
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