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Abstract #1779

Quantitative Assessment of Liver Function using Hepatocyte Fraction on Gd-EOB-DTPA-Enhanced MRI

Xueqin ZHANG1, Jian LU1, Jifeng JIANG1, Ding DING1, and Weibo CHEN2

1the Third People’s Hospital of Nantong, Nantong, China, 2Philips Healthcare, Shanghai, China

The purpose of this study was to investigate the ability of hepatocyte fraction on Gd-EOB-DTPA-enhanced MRI for the assessment of liver function of HBV-induced cirrhosis. We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 20 minutes after Gd-EOB-DTPA administration, hepatocyte fraction (HeF) and KHep values were measured. Our study showed that hepatocyte fraction is useful for the evaluation of liver function of HBV-induced cirrhosis.

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