We aimed to investigate if a stretched exponential diffusion weighted imaging model (SEM) can be applied to assess nonalcoholic liver disease (NAFLD) disease by providing distributed-diffusion-coefficient (DDC) and α separately evaluating mean intravoxel diffusion rate and diffusion heterogeneity. The SEM model was then applied to analyze NAFLD in a rabbit model and compared with a mono-exponential (ME) model. While DDC from the SEM model showed comparable values with apparent-diffusion-coefficient (ADC) estimated in the ME model, alpha indicated more robust performance in the diagnosis of nonalcoholic steatohepatitis (NASH). Therefore, SEM model showed a great potential in early diagnosis of NASH.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords